We evaluate the impact of oral bile replacement during external biliary drainage on the regenerative capabilities of instentinal mucosa, focusing on enterocytic integrity and mucosa barrier function. The drained biliary fluid undergoes a series of mechanical filtrations with progressively smaller porosity to reduce the bacterial load. The primary clinical markers observed during the therapy include biliary bile acids and phospholipids, serum citrulline, and serum diamine oxidase. Due to the low specificity of these markers for the function of intestinal mucosa, the clinical assay also includes additional clinical analytes.
- Rock Climbing Physics: The Fundamental Mechanisms (book)
- Epidemiological Analysis of 2019 Wuhan Coronavirus Outbreak